Jay and Margie Grosfeld Symposium

- EDT

 Presented by the APSA Research Committee
• Advances in the Treatment of Lung Hypoplasia and Inflammation
• Determinants of Pulmonary Function
• Outcome of Children with Neuroblastoma
Announcement of 2021 Jay Grosfeld, MD Scholar Grant Recipients

Moderators: 

Shaun M. Kunisaki, MD, MSc, Johns Hopkins Hospital, Baltimore, MD, USA

Agostino Pierro, MD, The Hospital for Sick Children, Toronto, ON, Canada

PROGRAM

Abstracts

  • Human Amniotic Fluid Stem Cell Derived Extracellular Vesicles Restore Branching Morphogenesis and Epithelial Progenitor Cells in a Novel Model of Human Pulmonary Hypoplasia
  • CNP-miR146a Reduces Lung Inflammation and Fibrosis Following Acute Injury
  • What’s Wrong with Hypoplastic Lungs of Fetuses with Congenital Diaphragmatic Hernia? Transcriptomic Profiling of The Pulmonary Epithelium from Fetal Hypoplastic Lungs
  • Congenital Diaphragmatic Hernia Associated Pulmonary Hypoxia and Inflammation are Initiated in Utero
  • Heparin and Enoxaparin Impair Pulmonary Function After Murine Left Pneumonectomy
  • High Ras Expression is Associated with Poor Neuroblastoma Patient Survival and Required for Tumor Formation in an Orthotopic Mouse Model
  • Protein Phosphatase 2A Activation Decreases Tumorigenicity in Neuroblastoma Patient Derived Xenografts
  • Chemokine Receptor CXCR4 Mediates the PIM3-Induced Metastatic Phenotype of Hepatoblastoma Cells
  • Oncolytic Herpes Simplex Virus Effectively Targets and Kills Neural Crest Patient-Derived Xenografts
  • Induction of SHMT2 Promotes Tumorigenesis in High-Risk Neuroblastoma

Presentations by Research Committee Members

BASIC AND TRANSLATIONAL RESEARCH IN CONGENITAL DIAPHRAGMATIC HERNIA

Shaun M. Kunisaki, MD, MSc, Johns Hopkins Hospital, Baltimore, MD, USA

HOW EMBRYONAL TUMOR BIOLOGY DRIVES RISK ASSIGNMENT

Harold N. Lovvorn, MD, Vanderbilt University Medical Center, Nashville, TN, USA