Health Supernova 2022 Health Supernova 2022

Concurrent Session

Tuesday, May 10, 2022

- CDT
Lightning Talk | 3D Printed Surgical Models
Smriti Zaneveld
Smriti Zaneveld
Lazarus 3D, President & Founder

As the saying goes, practice makes perfect. From poultry and fruit to life-sized human mannequins, surgeons spend years practicing techniques before they enter the operating room. Yet every patient is unique, and it’s been virtually impossible to practice the particulars of an intricate surgery in advance — until now.

The team at Lazarus 3D is transforming preoperative care by allowing surgeons to rehearse surgeries in advance on realistic, 3D-printed models of an individual patient. Made with soft silicones and hydrogels that mimic human tissue, these models are ideal for practicing incisions and sutures — maximizing safety and driving better outcomes for patients and physicians alike. Learn more about this technology and its implications in this quick Lightning Talk with Lazarus 3D President and Founder Smirti Agrawal Zanevald.

- CDT
Lightning Talk | Precision Pain Therapeutics
Candler Paige
Candler Paige
Doloromics, CEO

“No pain, no gain” is meant to console and motivate. Yet, for millions who live with unrelenting debilitating conditions, they’d do anything to gain relief. Opioids can’t be the only answer. Every day in America, three people die every hour from opioid overdose. Prescription opioid misuse alone costs the U.S. $78.5B a year for healthcare, addiction treatment, and more. Physicians need other options and other prospects to help patients manage their pain.

CEO Candler Paige is on a mission to help. Her company, Doloromics, is building a proprietary platform for discovery of disease-specific pain mechanisms, biomarkers, and therapeutics to treat inflammatory and chronic pain. It will be a game-changer for getting quick chronic pain relief to patients who suffer from migraine, muscle pain, and neuropathies — common problems that require uncommon solutions.

- CDT
Lightning Talk | Reconstructing Prosthetics Technology
Connor Glass
Connor Glass
Phantom Neuro, Founder & CEO

The global prosthetics and orthotics market was valued at ~$6B in 2020 and is expected to grow at a CAGR of 4.2% through 2028. Those figures aren’t surprising. The World Health Organization estimates that 30 million people are in need of prosthetic and orthotic devices right now. That number grows annually, with 185,000 Americans alone suffering the loss of a limb each year. But the prosthetics of tomorrow have the potential to work (and look) far different from those we use today — changing the market as well as the lives of millions.

In this Lightning Talk, Connor Glass will share how his team at Phantom is building a system to help people gain lifelike control of robotic limbs through a unique human-machine interfacing system. This technology, based in reconstructive surgery research at Johns Hopkins, combines small implantable sensors, AI, and software in an effort to allow people to control robotic prostheses and exoskeletons using existing muscles near the location of the amputation.


- CDT
Lightning Talk | AI-Based Neural Insights
Dexter Ang
Dexter Ang
Pison, Executive Chairman and Founder

ALS, or Lou Gehrig’s disease, has a devastating effect on quality of life. What began as an effort to help ALS patients control their extremities with digital interfaces has evolved into a patented electroneurography platform that allows for first-of-its-kind intuitive control of any experience in the IoT universe.

In this Lightning Talk, hear founder Dexter Ang talk about the breakthrough Pison platform. Pison leverages machine learning to interpret the intent of the microvoltage that courses through the human body when our brains communicate with our muscle systems. The applications ahead? Sophisticated prosthetics. Touchless robotics. Sensitive interfaces. Smart(er) home controls. And so much more. 

- CDT
Lightning Talk | Objective Mental Health Diagnosis
David Zakariaie
David Zakariaie
Senseye, Inc., CEO/Founder

Depression and anxiety rates climbed by more than 25% worldwide in 2020. Yet these numbers were already alarmingly high, with millions suffering from a range of anxiety and depressive disorders along with related struggles in addiction that often accompany these conditions. Post-traumatic Stress Disorder (PTSD) alone affects 7.7 million adults in the United States, approximately 3.5% of the population. Yet the standard of care for mental health diagnosis today is keyed to subjective questionnaires and conventional tests, which take hours to complete and depend solely on patient responses to form a diagnosis. For this and other reasons, millions of those struggling with depression, anxiety, and addiction go undiagnosed and untreated.

To help close this gap in care, Senseye is building a breakthrough diagnostic platform for mental health, starting with PTSD. Using computer vision technology, this tool allows clinicians to gather insights by tracking disruptions in the sympathetic nervous system through the eyes. CEO David Zakariaie will share his vision for the platform, which can be used remotely though widely available smartphone technology to inform a truly objective diagnosis in as little as 10 minutes.

- CDT
Lightning Talk | Platform Approaches to Combating Diseases
Benjamin M. Greenberg
Benjamin M. Greenberg
UT Southwestern, Professor of Neurology
David Greenberg
David Greenberg
UT Southwestern, Professor, Infectious Diseases and Microbiology

What began as endless battles with action figures is now an endless and inspiring crusade to prevent and fight disease. In this Lightning Talk, two brothers at UTSW Medical Center —one an Infectious Disease expert trained at NIH, the other a Johns Hopkins-trained Neuroimmunologist—are on separate but driven paths.

Meet Dr. David Greenberg who is focused on commercializing precision pathogen-specific antibiotics to help tackle the worldwide crisis of antibiotic resistance. And learn about Dr. Ben Greenberg’s efforts for the Department of Neurology in treating rare autoimmune disorders of the central nervous system.

- CDT
Lightning Talk | Transforming Home Care Through Machine Learning presented by AWS Web Services, Inc.
Amanda L. Goltz
Amanda L. Goltz
Amazon Web Services, US Healthcare Lead for Worldwide Public Sector Healthcare Venture Capital and Startups

Machine learning and behavioral analytics are transforming patient care in hospitals and clinics. Now, these same technologies are set to transform home care, as well. Through wearable devices and other sensors, ML-driven solutions can analyze data to spot when an individual’s behavior deviates from the norm, flagging providers who can intervene early and take appropriate action. And that’s just the beginning.

Amazon Web Services has been on the forefront of using voice applications to move healthcare out of primary health institutions and into homes. Amanda Goltz will cover how technology is adopted in healthcare, what other industries can learn from those innovations, and why healthcare needs pioneers in AI/ML and robotics. She will also discuss how to focus on prevention — even  when there doesn’t seem to be a strong buyer in today’s healthcare system — and why that strong buyer doesn’t exist. 

- CDT
Lightning Talk | Reviving the Wooly Mammoth
Brandi Cantarel
Brandi Cantarel
Colossal, Associate Director of Bioinformatics

How are the genomes of mammoths different from their closest living relatives? And what genetic changes impact physical and adaptive traits? These are the types of questions bioinformaticians seek to answer by using next-gen tools to help design, execute, and validate biological experiments. And they’re questions that Brandi Cantarel and Colossal are answering to turn back time and revive the wooly mammoth. But it's not just about the species; this set of tools can be used for many purposes, whether it’s de-extinction or re-coding the human genome

In this quick talk, Brandi will outline how Colossal is pioneering CRISPR technology for the purposes of species de-extinction, beginning with the wooly mammoth. She and her team are combining the science of genetics with the business of discovery in an endeavor to jumpstart nature’s ancestral heartbeat and advance the economies of biology and healing through genetics. 

- CDT
Lightning Talk | Rewiring the Brain to Enhance Recovery
Robert L Rennaker II
Robert L Rennaker II
Xnerve Medical, CEO

The human brain can generate incredibly complex and beautiful behaviors. These behaviors are driven by neural patterns that have been developing throughout our lifetimes. Yet, following neurological injuries, the neural circuits in our brain change. While some of these changes are helpful and account for functional recovery, maladaptive changes can result in spasticity, chronic pain, tinnitus, phantom limb pain, and other neurological conditions that negatively impact the quality of life.

Robert Rennaker will discuss the use of vagus nerve stimulation to enhance recovery of motor function following spinal cord injury and stroke and to treat post-traumatic stress disorder. His company, X-Nerve, is currently running three clinical trials with a wireless glass encapsulated, ultra-miniature, MRI compatible stimulator that never needs to be replaced.  The device is powered by a wearable that can be triggered via Bluetooth, allowing the rapid development of rehabilitation and treatment tools that can take advantage of Targeted Plasticity Therapy. Their goal? To ensure this therapy maximizes recovery, reduces the need for future surgery, and (most importantly) does not prevent the standard of care.

- CDT
Lightning Talk | Objective Mental Health Diagnosis (TAKE TWO!)
David Zakariaie
David Zakariaie
Senseye, Inc., CEO/Founder

Concurrent sessions can make it tough to choose when there’s so much great content being presented. That’s why David Zakariaie has agreed to give this talk not just once but TWICE! And It’s one you don’t want to miss. ↓

Depression and anxiety rates climbed by more than 25% worldwide in 2020. Yet these numbers were already alarmingly high, with millions suffering from a range of anxiety and depressive disorders along with related struggles in addiction that often accompany these conditions. Post-traumatic Stress Disorder (PTSD) alone affects 7.7 million adults in the United States, approximately 3.5% of the population. Yet the standard of care for mental health diagnosis today is keyed to subjective questionnaires and conventional tests, which take hours to complete and depend solely on patient responses to form a diagnosis. For this and other reasons, millions of those struggling with depression, anxiety, and addiction go undiagnosed and untreated.

To help close this gap in care, Senseye is building a breakthrough diagnostic platform for mental health, starting with PTSD.  Using computer vision technology, this tool allows clinicians to gather insights by tracking disruptions in the sympathetic nervous system through the eyes. CEO David Zakariaie will share his vision for the platform, which can be used remotely though widely available smartphone technology to inform a truly objective diagnosis in as little as 10 minutes.

- CDT
Lightning Talk | Ending the Antibiotic Abuse presented by University of North Texas Health Science Center at Fort Worth
Joe Skraba
Joe Skraba
Entvantage Diagnostics, Inc., Co-Founder, President and CEO

80% of patients are prescribed antibiotics for sinusitis, yet 90% of the time, sinusitis is caused by a viral infection that is untreatable by antibiotics. Together Entvantage Dx can reduce the use of antibiotics for ear, nose, and throat illnesses. Entvantage Dx diagnostic tests accurately distinguish bacterial from viral infections, reducing the unnecessary prescription of antibiotics. Joe Skraba will talk about their revolutionary diagnostic kit can qualitatively identify the three major bacterial sinusitis pathogens and provide differentiation from viral sinusitis infections. This determination allows the physician to only prescribe antibiotic treatment for patients who have bacterial sinusitis. 

- CDT
Lightning Talk | The 3 Tenets of Transformation presented by McKesson
Christy O'Gaughan
Christy O'Gaughan
McKesson, VP of Data and Digital Innovation

Healthcare in the wake of COVID-19 requires new ways of thinking about virtually every aspect of the U.S. healthcare system. An aging population. Chronic disease patterns. Accessibility. Equity. And of course, cost. So what does transformation really require?

Christy O’Gaughan led a global digital transformation during COVID, embracing three core tenets of transformation — the importance of unlearning, the ability to think several steps ahead, and the power of using your network to achieve greater outcomes. Lean in with Christy for her detailed perspective on what it takes and how to make it happen. 

- CDT
Robotics to Empower Patient Care
Carisa Raucci
Carisa Raucci
Diligent Robotics, Director of Operations

For most nurses, their primary role and motivation is to advocate for patients, care for individuals, and support people through health and illness. Yet 30% of their time is spent on routine tasks, many of which can be addressed through technology. With the number of nurses leaving the workforce each year growing steadily — from around 40,000 in 2010 to nearly 80,000 by 2020 — implementing new technologies now could lower the burden on nurses while improving the overall quality of patient care.

Carisa Raucci from Diligent Robotics is working to be part of that solution. She and her team develop robots that are designed to support and work together with clinical teams so they can focus on caring for patients. In this quick session, Carisa will give you a peek at “Moxi,” a socially intelligent robot that can aid nurses without making humans feel uncomfortable.

- CDT
Social Determinants of Health in the Age of Digital Health Care presented by BlueCross BlueShield of Texas | C1 Innovation Lab
Claire Aldridge
Claire Aldridge
Taysha Gene Therapies, Senior Vice President
Madhuri Bobba
Madhuri Bobba
Senior Executive Medical Director, Blue Cross and Blue Shield of Texas

As technologies rise to improve healthcare, so too must our societal approaches to ensure all have equitable access to optimal healthcare, as well as access to key social and community services that contribute to positive health outcomes. 

All of us, from clinicians to business executives, technologists, and community leaders each play an important role in impacting the social determinants of our society. 

Join Dr. Madhuri Bobba and Dr. Claire Aldridge for a discussion about how technologies and social systems can work together to help people thrive in their health and lives.

- CDT
The Digital Revolution in Healthcare
Smriti Zaneveld
Smriti Zaneveld
Lazarus 3D, President & Founder
Lauren Tyra
Lauren Tyra
Green Park & Golf Ventures, Chief Scientific Officer
Amanda L. Goltz
Amanda L. Goltz
Amazon Web Services, US Healthcare Lead for Worldwide Public Sector Healthcare Venture Capital and Startups
Christy O'Gaughan
Christy O'Gaughan
McKesson, VP of Data and Digital Innovation

You don’t want to miss this Digital Health Track panel. Hear from four visionaries who are thinking — and acting — outside the box to create revolutionary solutions to improve health options and outcomes.

Technology has been the driving force behind unprecedented innovation in patient care. The COVID-19 pandemic accelerated this trend and renewed focus on utilizing technology to expand access to care, particularly among underserved and high-risk populations. Hear these visionaries discuss what they and others are doing with AI/machine learning, wearable devices and other sensors, 3D printing, computer vision, and more to help transform patient care in hospitals, clinics, and at home. 

- CDT
The Brain as a Computer Interface
Matt Angle
Matt Angle
Paradromics, CEO

The brain is a data organ. Everything we touch and everything we experience comes as information to the brain. Similarly, everything we do comes as signals from the brain. The input and output of the brain is information. So could computer chips that connect directly to the brain give sight to people who are blind — or even eliminate mental illness?

Matt Angle and his Paradromics Inc. team are making the brain accessible to direct communication with computers, advanced sensors, or any digital device. As keynote speaker for our Medical Devices track, Matt will discuss their work and offer insights on the role human augmentation and robotics will play in the future of health — a global market that is expected to reach $665B by 2028.

- CDT
A Better Way to Treat Brain Tumors
Darin T. Okuda
Darin T. Okuda
UTSW Medical Center, Professor of Neurology, Director of Neuroinnovation

Weighing in at just three pounds, the human brain is the marvelous, mysterious source of everything that defines us as humans. It’s also been the modern medical mystery for centuries, and only in the last 10 years or so has scientific research yielded important insights and answers. Now, as technology development accelerates, exciting breakthroughs in neurological and behavioral science are possible.

That’s welcome news for more than 700,000 Americans living with a primary brain tumor. While most brain tumors are not malignant, the impact of treatment is likely life-changing. Dr. Darin Okuda and his team at UT Southwestern Neurology are working to change these realities, with a better way to diagnose and treat brain tumors using 3-D printing. As the keynote speaker for our Genesis of Prevention track at Health Supernova, presented by The University of Texas at Dallas and UT Southwestern Medical Center, Dr. Okuda will share how it works — and how it can scale.

- CDT
Incubating Biotech Innovation
Fiona Mack
Fiona Mack
Johnson and Johnson, Regional Director JLABS

The momentum in digital health is escalating, as the world adjusts to new, lasting realities. JLABS is driving the innovation required. Ever since it debuted in 2012, this incubator division of Johnson & Johnson has championed dozens of budding biotech companies that are innovating across digital health and other areas. Today, JLABS is a global network of open innovation ecosystems.

In this keynote, Fiona Mack shares insights on how JLABS provides tools, infrastructure, and mentoring to help startups take their ideas forward. She’ll showcase exciting activities underway, such as their virtual JLABS model, and talk about crucial efforts to empower innovators to incorporate health equity into early research.